Walton attended the University of Notre Dame, and played for the Notre Dame Fighting Irish football team from 1999 to 2002. He originally attended Notre Dame on a soccer scholarship and was named Big East Freshman of the Year after leading the soccer team in scoring in 1998. He walked on to the Irish football team as a sophomore, and was recognized as a unanimous first-team All-American as a senior in 2002. Walton finished the year with 68 tackles (46 solo), seven interceptions (two returned for touchdowns) and seven pass breakups.
Walton currently works as a behavioral analyst with F.I.T. and coaches at his alma mater, The Bishop's School.
Walton heads the Shane Walton Foundation that funds tutors for children attempting to become eligible for private schools in San Diego.
He continues playing adult soccer for the Nomads and other teams in the San Diego area.