From 2004 to 2018, Mayock worked with the NFL Network. Between 2001 and 2004, Mayock served as a college football analyst for ABC Sports. Prior to ABC, he called college football action for Fox Sports Net during the 2000 season, after four years (1996–99) as a member of CBS Sports' broadcast team—during which time he served as both a game analyst (1996, '97 and '99) and lead sideline reporter (1998). Mayock also worked as a reporter for CBS's coverage of the NCAA basketball tournament in 1997, '98 and '99.
He joined CBS from ESPN, where he worked as an analyst and sideline reporter for the cable network's coverage of the Canadian Football League and college football from 1993–95. Additionally, Mayock has experience covering college football for Prime Network, NCAA Productions, Prime Sports Radio and the Big East Conference.
He was the color commentator for the Minnesota Vikings pre-season games for several seasons. From 2015 to 2018, Mayock commentated on the Philadelphia Eagles preseason television broadcasts alongside play-by-play announcer Scott Graham and sideline reporter Dave Spadero.