Herron moved to the NFL in 1973, when he joined the New England Patriots. He later played for the Atlanta Falcons. In three seasons, he gained 1,298 rushing yards and scored 9 rushing touchdowns. He also caught 61 passes in his career for 789 yards and 6 touchdowns.
After leading the NFL in kickoff returns and kickoff return yardage in 1973, Herron's best season was 1974 with the Patriots, when he set the then-NFL record for all-purpose yards with 2,444. The Patriots released him midway through the following season, with coach Chuck Fairbanks claiming the release was the result of disappointment with Herron's performance that season and with a late night party Herron threw for teammate Leon Gray. He was then signed by the Falcons. He remains 16th all time in career punt return average and 86th in kickoff return average. In 2009, he was named by the Patriots Hall of Fame nomination committee to the Patriots All-Decade Team for the 1970s as a kick returner.
Herron, a devout Muslim who did not drink or smoke, was arrested some 20 times and served jail time, mainly on drug convictions, according to Chicago Police. He died on December 6, 2015, at the age of 67.