In 1971, his five-year-old daughter Kim (August 11, 1966 – March 5, 2011) was diagnosed with leukemia. His teammates, general manager Jim Murray, and team owner Leonard Tose rallied around the family. In the aftermath of her successful treatment, the team in 1972 initiated the Eagles Fly for Leukemia philanthropic program, and Hill, Murray, and teammates co-founded the very first Ronald McDonald House, which opened in Philadelphia in 1974. Kim Hill died in 2011.
The Eagles had a tie-in with McDonald's Shamrock Shake. By donating a share of every shake sold to the Eagles Fly for Leukemia, McDonald's acquired naming rights.
At one home game each season, the Eagles pass a bucket in the stands for donations to the Eagles Fly for Leukemia charity.