"Crazy on You" is the guitar-driven debut single from the female-fronted (Nancy and Ann Wilson) rock band Heart's debut album Dreamboat Annie, released in 1976. Starting with an acoustic guitar intro called "Silver Wheels", the song turns into fast-paced rock song that was the signature sound of the band in their early years. "Crazy on You" attracted attention both for the relatively unusual combination of an acoustic guitar paired with an electric guitar, and the fact that the acoustic guitarist was a female – a rarity in rock music during that time. According to co-writer/guitarist Nancy Wilson on an episode of In the Studio with Redbeard (which devoted an entire episode to the Dreamboat Annie album), the rapid acoustic rhythm part was inspired by The Moody Blues song "Question".
The song's lyrics tell of a person's desire to forget all the problems of the world during one night of passion. During an interview on Private Sessions, Ann Wilson revealed the song was written in response to the stress caused by the Vietnam War and social unrest in the United States in the early seventies.
"Crazy On You" became the band's first commercial hit, peaking at #35 on the charts in the summer of 1976. Despite its modest chart, "Crazy on You" remains as one of Heart's signature tunes and is still a staple on U.S. classic rock radio stations. In late 1977, Mushroom Records re-released the single with the same catalog number and B-Side. This re-release peaked at #62 on the Hot 100 in early 1978. In the Netherlands it reached number two on the singles chart in March 1977. The single's B-side, "Dreamboat Annie", was later released on its own as an A-side.
It is featured in the 2007 film Juno, and is mentioned in the credits. However, it does not appear on the soundtrack.
CBS used the guitar riff from this song when going to a commercial break on its NFL coverage during the 1980 NFL season. It was also heard during the NBA on CBS broadcast during the 1979-80 and 1980-81 NBA Seasons.