|No. 28 Toronto Argonauts|
|Date of birth:||December 11, 1984|
|Place of birth:||Blackville, South Carolina|
|Height:||6 ft 3 in (1.91 m)|
|NFL Draft:||2008 / Undrafted|
* Pre-season or practice roster only
|Playing stats at|
Brandon Isaac (born December 11, 1984 in Blackville, South Carolina) is a professional Canadian football linebacker for the Toronto Argonauts of the Canadian Football League. He signed as a free agent with the Argonauts on May 8, 2012. Isaac was a member of the 100th Grey Cup winning team. He also played college football for the South Carolina Gamecocks.