Duhe is probably best remembered for his performance in the 1982 AFC Championship Game against the New York Jets at the Orange Bowl in Miami. The game was known as the Mud Bowl, with the field doused in water and mud after a heavy rainstorm. At halftime, the score was 0-0. In the second half, Duhe intercepted three of Jets quarterback Richard Todd's passes, including one he returned 35 yards for a touchdown in the fourth quarter, to help the Dolphins to a 14-0 victory which sent them to Super Bowl XVII.
Duhe made his acting debut in the episode "Walk-Alone" of the series Miami Vice.
He also played the Cleveland linebacker in the 1988 movie Everybody's All-American