Florida got on the board first, only 2 minutes into the game, when Tremaine McCollum blocked an Iowa punt, and returned it 6 yards for a touchdown. That was the only scoring of the first quarter. In the second quarter, Iowa stopped Florida inside its own five yard line, but Florida got a field goal from kicker Chris Hetland, to go up 10-0. With 1:57 left in the half, and Iowa driving, Iowa quarterback Drew Tate was intercepted by cornerback Vernell Brown, who returned it 60 yards for a touchdown, and a 17-0 lead.
Iowa came right back though, as quarterback Drew Tate found wide receiver Clinton Solomon for a 20 yard touchdown pass, to trim the lead to 17-7 with 1:10 to go in the half. It was enough time for Florida however, as Florida scored its first offensive touchdown of the game. Quarterback Chris Leak found wide receiver Dallas Baker for a 24 yard touchdown pass with 1 second left in the half, as Florida took a 24-7 lead into the locker room.
With 5:23 left in the third quarter, Florida seemingly put the game away, with a 38 yard touchdown pass from Leak to Baker, to put Florida up 31-7, but Iowa would come back. Early in the fourth quarter, Drew Tate found wide receiver Ed Hinkel for a 4 yard touchdown pass to trim the margin to 31-14. With less than 7 minutes to play, Tate again found Hinkel, this time for a 14 yard touchdown pass, as Iowa drew within 31-21. Iowa stopped Florida once again, and got the ball back.
With 1:24 left in the game, Kirk Ferentz decided to kick a field goal, since they were down 2 possessions anyway. Kyle Schlicher kicked a 45 yard field goal, to make it a one possession game. His onside kick attempt was recovered by Iowa, but Iowa was controversially flagged for being offside, and Florida regained possession on the subsequent attempt.