Alabama opened the season with a victory over Louisiana Tech in Birmingham and followed that with a victory at Ole Miss for their first conference win of the season. The Crimson Tide then returned home and defeated Clemson in the first Tuscaloosa game of the season before they traveled to Knoxville for their annual rival game against Tennessee. In the game, Alabama trailed the Volunteers 10–0 in the fourth quarter before they rallied for an 11–10 victory that saw Tennessee miss a game-winning field goal in the final minute of play.
Alabama then alternated home games between Birmingham and Tuscaloosa over the next four weeks and defeated Vanderbilt, Mississippi State, LSU and South Carolina in each game. After they defeated Southern Miss in their annual Mobile game, the Crimson Tide defeated Auburn in the Iron Bowl and captured a share of the SEC championship. In the January that followed, Alabama then defeated Nebraska in the Sugar Bowl and finished the season undefeated. Although they were the only undefeated and untied college team at the conclusion of the year, Alabama was not selected as national champions for the season. On the 1966 squad, Green Bay Packers head coach Vince Lombardi stated: "I don't know, we haven't played Alabama yet" when asked how it felt to have the world's greatest football team for the season after his Packers won Super Bowl I.
Alabama was recognized as national champions from the Associated Press for the 1965 season after they defeated Nebraska in the Orange Bowl and finished with an overall record of 9–1–1. In February 1966, SEC commissioner Bernie Moore penalized Alabama for scholarship violations with its freshman squad. Moore found that Alabama awarded 42 freshman scholarships instead of the 40 allowed by the league. As such, the Crimson Tide were penalized with a scholarship reduction of two to 38 for the 1966 recruiting class.
To open the 1966 season, the No. 3 Crimson Tide defeated the Louisiana TechBulldogs 34–0 in the first all-time meeting between the schools on the football field. After a scoreless first quarter, Alabama took a 14–0 halftime lead on a 32-yard Ken Stabler touchdown pass to Dennis Homan and on an eight-yard Stabler touchdown run. After a two-yard Harold Moore touchdown run in the third, the Crimson Tide made the final score 34–0 in the fourth after they scored on a 79-yad Stabler pass to Homan and on a four-yard Moore run.
Prior to their game against Ole Miss, Alabama retained the No. 3 position in the AP Poll, and on a Saturday evening, the Crimson Tide defeated the Rebels 17–7 at Jackson. After a scoreless first quarter, Alabama took a 7–0 halftime lead when Leslie Kelley scored on a one-yard touchdown run with only 0:40 left in the quarter. The Crimson Tide then extended their lead further to 14–0 in the third quarter when Ken Stabler threw a 28-yard touchdown pass to Ray Perkins. The Rebels responded early in the fourth and cut the Crimson Tide lead in half when Julian Cunningham scored on a two-yard touchdown run, and then Alabama closed the game with a 21-yard Steve Davis field goal that made the final score 17–7. The victory improved Alabama's all-time record against Ole Miss 19–3–2.
After their closer-than-expected victory over Ole Miss, Alabama dropped into the No. 4 position in the AP Poll prior to their game against Clemson. In what was their first game against the Tigers since the 1936 season, who were led by former Crimson Tide player Frank Howard as head coach, Alabama won 26–0. The Crimson Tide took a 6–0 first quarter lead when Ken Stabler threw an eight-yard touchdown pass to Dennis Homan. They then extended their lead to 16–0 at halftime after a 32-yard Steve Davis field goal and one-yard Stabler touchdown run in the second quarter. Alabama then closed the game with an eight-yard Stabler touchdown pass to Kenny Martin in the third and a 36-yard Davies field goal in the fourth quarter that made the final score 26–0. The victory improved Alabama's all-time record against Clemson to 7–3.
After their victory over Clemson, Alabama regained the No. 3 position in the AP Poll prior to their game against Tennessee. At a rain-soaked Neyland Stadium, Alabama overcame a 10–0 fourth quarter deficit and defeated the rival Volunteers 11–10 and preserved their perfect record. Tennessee scored all of their points in the first quarter. The first points came on a six-yard Dewey Warren touchdown pass to Austin Denney and next on a 40-yard Gary Wright field goal for a 10–0 lead. Still up by 10, the Crimson Tide made their comeback in the fourth quarter. Ken Stabler scored on a one-yard touchdown run and then successfully converted the two-point conversion on a short pass to Wayne Cook that made the score 10–8. With 3:23 left in the game, Steve Davis kicked the 17-yard, game-winning field goal that made the score 11–10. The Volunteers did manage to set up a 19-yard field goal attempt that went wide in the final 0:20 of the contest. The victory improved Alabama's all-time record against Tennessee to 23–19–7.
After their victory over Tennessee, Alabama again dropped into the No. 4 position in the AP Poll prior to their game against Vanderbilt. Against the Commodores, Alabama played 56 different players in their 42–6 victory at Birmingham. The Crimson Tide took a 21–0 first quarter lead before Vanderbilt scored their only points of the game. Alabama touchdowns were scored by Bobby Johns on a 40-yard interception return, a 29-yard Leslie Kelley pass to Ray Perkins on a halfback option play and on a 35-yard Wayne Trimble pass to Richard Brewer. The Commodores responded with their only points on a three-yard Roger May touchdown pass to Steve Skupas late in the first. A 14-yard David Chatwood touchdown run in the second quarter made the halftime score 28–6 in favor of Alabama. The Crimson Tide then closed the game with a pair of third-quarter touchdowns on an 18-yard Trimble pass to Dennis Homan and on a one-yard Trimble run. The victory improved Alabama's all-time record against Vanderbilt to 24–16–4.
At Denny Stadium, the Crimson Tide traded touchdowns in the fourth quarter and defeated the Mississippi StateBulldogs 27–14 in Tuscaloosa. After a scoreless first quarter, Alabama took a 10–0 halftime lead after a 35-yard Steve Davis field goal and a 26-yard Wayne Trimble touchdown pass to Ray Perkins. Davis then added a 31-yard field goal in the third before both teams traded touchdowns in the fourth quarter and made the final score 27–14. In the final quarter, the Crimson Tide scored on Trimble touchdown passes of 48-yards to Jerry Duncan and 38-yards to Perkins; Mississippi State scored on a three-yard Prentis Calhoun run and on an 11-yard Don Saget pass to Calhoun. The victory improved Alabama's all-time record against Mississippi State to 38–10–3.
After their victory over Mississippi State, Alabama retained the No. 4 position in the AP Poll prior to their game against LSU. Behind a strong defensive performance, the Crimson Tide defeated the Tigers 21–0 at Legion Field. Alabama took a 5–0 first quarter lead after Mike Hall blocked a Mitch Worley punt for a safety and Steve Davis connected on a 24-yard field goal. Davis then made the halftime score 8–0 in favor of the Crimson Tide with a 32-yard field goal. In the third quarter, Bobby Johnsintercepted a Fred Haynes pass and returned it 33-yards for a touchdown and in the fourth a three-yard Frank Canterbury touchdown run made the final score 21–0. The victory improved Alabama's all-time record against LSU to 18–8–4.
On homecoming in Tuscaloosa, Alabama defeated the South CarolinaGamecocks 24–0 at Denny Stadium. The Crimson Tide took a 14–0 halftime lead after touchdown runs of one-yard by David Chatwood in the first and of three-yards by Leslie Kelley in the second quarter. Alabama then closed the game with a 13-yard Wayne Trimble touchdown pass to Ray Perkins in the third and on a 31-yard Steve Davis field goal in the fourth that made the final score 24–0. The victory improved Alabama's all-time record against South Carolina to 6–0.
In their annual game played at Mobile, Alabama shutout the Southern MissGolden Eagles 34–0 at Ladd Stadium. After a scoreless first, the Crimson Tide took a 12–0 halftime lead on a pair of Ken Stabler touchdown passes. The first was from 25-yards to Ray Perkins and the second from one-yard out to Wayne Cook. After a 13-yard David Chatwood touchdown run in the third, Alabama then closed the game with a pair of touchdowns and two-point conversions in the fourth quarter. The first came on a 55-yard Stabler touchdown pass to Dennis Homan and the second on a one-yard Joe Kelley run that made the final score 34–0. The victory improved Alabama's all-time record against Southern Miss to 8–2–1.
In the annual Iron Bowl game, Alabama defeated the AuburnTigers 31–0 and secured their third consecutive SEC championship. After a scoreless first quarter, the Crimson Tide took a 17–0 halftime lead with points scored on a 63-yard Ken Stabler touchdown pass to Ray Perkins, on a one-yard Leslie Kelley run and on a 23-yard Steve Davis field goal. Alabama then concluded their scoring with a pair of third-quarter touchdowns on a 12-yard Kelley run and on a 41-yard Wayne Trimble pass to Donnie Sutton that made the final score 31–0. The victory improved Alabama's all-time record against Auburn to 16–14–1.
For the second year in a row, Alabama played Nebraska in their bowl game, and for the second consecutive year defeated the Cornhuskers. In the 1967 edition of the Sugar Bowl, the Crimson Tide defeated Nebraska 34–7 and finished the season undefeated. Alabama opened with a 17–0 lead in the first quarter on touchdown runs of one-yard by Leslie Kelley, 14-yards by Ken Stabler and on a 30-yard Steve Davis field goal. They then extended it to 24–0 at halftime after a six-yard Wayne Trimble touchdown run in the second quarter. After a 40-yard Davis field goal in the third for the Crimson Tide, Nebraska scored their only points early in the fourth quarter on a 15-yard Bob Churchich touchdown pass to Dick Davis that made the score 27–7. Alabama then closed the game with a 45-yard Stabler touchdown pass to Ray Perkins that made the final score 34–7. For is performance, Stabler was recognized as the game's MVP. The victory improved Alabama's all-time record against Nebraska to 2–0.
Prior to the 1972 NCAA University Division football season, NCAA rules prohibited freshmen from participating on the varsity team, and as such many schools fielded freshmen teams. The Alabama freshmen squad was led by coach Clem Gryska for the 1966 season and finished with a record of four wins and zero losses (4–0). The Baby Tide opened their season with a 27–14 victory over Mississippi State at Denny Stadium. After a scoreless first quarter, Alabama took a 7–0 lead in the second when Scott Hunter threw a five-yard touchdown pass to Tommy Wade. They then extended their lead to 17–0 at halftime when Mike Dean connected on a 46-yard field goal and Hunter scored on a short quarterback sneak. After Dean connected on a 31-yard field goal late in the third, the Bulldogs scored their first points late in the fourth on a 43-yard Dickie Carpenter touchdown run that made the score 20–7. Alabama responded with a 13-yard Wade touchdown run and State with a 13-yard Carpenter touchdown pass to George Davis that made the final score 27–14.
In their second game of the season, the Alabama freshmen defeated Ole Miss 31–14 at Oxford. Alabama took a 14–7 halftime lead with a pair of Tommy Wade touchdown runs from one and three-yards; Ole Miss scored their touchdown on a four-yard John Bowen run. After Mike Dean connected on a 25-yard field goal in the third, fourth-quarter touchdowns were scored for Alabama by Wade on a one-yard run and on a 20-yard Scott Hunter pass to Dean. The Rebels scored their final touchdown on a 40-yard Vernon Studdard pass to Louis Farber that made the final score 31–14. In their next game on November 7 against Tennessee, the Baby Tide won again by a score of 21–9. The Vols led 9–7 at halftime after Vic Dingus tackled Eddie Bentley in the endzone for a safety and on a 35-yard Mike Jones touchdown pass to Gary Kreis. Alabama's first half touchdown came on a 15-yard Tommy Wade run. The Baby Tide closed the game with touchdowns on a 13-yard Scott Hunter pass to Perry Willis in the third and on a two-yard Wade run in the fourth that made the final score 21–9.
In their final game of the season, Alabama defeated Auburn 6–3 at Denny Stadium and finished the season undefeated. After Joe Riley scored Auburn's only points with his 35-yard field goal in the first, Mike Dean scored all of the Tide's points with field goals of 20 and 31-yards.