1951 Kansas Jayhawks football team represented the University of Kansas in the Big Seven Conference during the 1951 college football season. In their fourth season under head coach Jules V. Sikes, the Jayhawks compiled an 8–2 record (4–2 against conference opponents), finished third in the Big Seven Conference, and outscored all opponents by a combined total of 316 to 208.  They played their home games at  Memorial Stadium in Lawrence, Kansas.
The team's statistical leaders included Bob Brandeberry with 649 rushing yards, Bud Laughlin with 78 points scored, and Jerry Robertson with 925 passing yards.
Aubrey Linville and  Bill Schaake were the team captains.
Date Opponent Rank Site Result
September 22 at TCU * W 27–13
September 29 Iowa State W 53–33
October 6 at Colorado No. 20 L 27–35
October 13 Utah * Memorial Stadium Lawrence, KS W 26–7
October 20 at No. 19 Oklahoma L 21–33
October 27 Kansas State Memorial Stadium Lawrence, KS ( rivalry) W 33–14
November 3 at Nebraska W 27–7
November 10 Loyola (CA) * Memorial Stadium Lawrence, KS W 34–26
November 17 at Oklahoma A&M * W 27–12
December 1 Missouri W 41–28 *Non-conference game Rankings from AP Poll released prior to the game