The 1949 Purdue Boilermakers football team was an American football team that represented Purdue University during the 1949 Big Nine Conference football season. In their third season under head coach Stu Holcomb, the Boilermakers compiled a 3–6 record, finished in eighth place in the Big Ten Conference with a 2–4 record against conference opponents, and were outscored by their opponents by a combined total of 175 to 126.[1][2]
Notable players from the 1949 Purdue team included tackle Lou Karras and fullback John Kerestes.