1921 Washington Pros (APFA)
| Day | Date | at | Opponent | Score | Location | Stadium | Attendance | |
|---|---|---|---|---|---|---|---|---|
| Sun | 10/09/21 | H | Hobart A.C. | Washington | DC | American League Park | Canceled | |
| Sun | 10/09/21 | H | Wilmington Collegians | 33- 0 W | Washington | DC | American League Park | |
| Sun | 10/16/21 | H | All-Lancaster A.C. | 33- 7 W | Washington | DC | American League Park | |
| Sun | 10/23/21 | H | Holmesburg A.C. | 0- 10 L | Washington | DC | American League Park | |
| Sun | 10/30/21 | A | Richmond A.C. | 10- 0 W | Richmond | VA | Boulevard Field | |
| Sun | 11/06/21 | H | Akron Goodyear Silents | - | Washington | DC | American League Park | Canceled |
| Sun | 11/06/21 | A | Norfolk | 61- 0 W | Norfolk | VA | ||
| Fri | 11/11/21 | A | Richmond A.C. | 0- 7 L | Richmond | VA | Boulevard Field | |
| Sun | 11/13/21 | H | Syracuse Pros | 20- 7 W | Washington | DC | National Park | |
| Sun | 11/20/21 | H | Clarksburg | 16- 7 W | Washington | DC | American League Park | |
| Sun | 11/27/21 | H | Canton Bulldogs | 0-15 L | Washington | DC | National Park | 4000 |
| Sun | 12/04/21 | H | Rochester Jeffersons | Washington | DC | National Park | 400 Forfeit by WAS? | |
| Sat | 12/10/21 | A | Baltimore Pros | 3- 10 L | Baltimore | MD | Wakbrook Oval | 500 |
| Sun | 12/11/21 | H | Cleveland Tigers | 7- 0 W | Washington | DC | National Park | 5000 |
| Sat | 12/17/21 | A | Richmond A.C. | 0- 41 L | Richmond | VA | Boulevard Field | 5000 |
| Sun | 12/18/21 | H | Canton Bulldogs | 14-28 L | Washington | DC | National Park | 3500 |
| Mon | 12/26/21 | H | Washington All-Stars | 16- 7 W | Washington | DC | American League Park |