1921 Oklahoma A&M Aggies football team

The 1921 Oklahoma A&M Aggies football team represented Oklahoma A&M College in the 1921 college football season. This was the 20th year of football at A&M and the first under John Maulbetsch. The Aggies played their home games at Lewis Field in Stillwater, Oklahoma. They finished the season 5–4–1, 1–1 in the Southwest Conference.