1973 Iowa State Cyclones football team

The 1973 Iowa State Cyclones football team represented Iowa State University in the Big Eight Conference during the 1973 NCAA Division I football season. In their first year under head coach Earle Bruce, the Cyclones compiled a 4–7 record (2–5 against conference opponents), tied for sixth place in the conference, and outscored opponents by a combined total of 245 to 236. They played their home games at Clyde Williams Field in Ames, Iowa.

Larry Hunt and Keith Krepfle were the team captains.