October 24, 1920

{| class="wikitable" cellpadding="14" border="2" ! colspan="8" align="center" | October 24, 1920
 * - bgcolor="#D0E7FF"
 * colspan="8" align="center" | Week 5
 * - bgcolor="#efefef"
 * - align="center"
 * Cleveland Tigers (0-2-1) || 0 || Akron Pros (4-0-0) || 7 || Akron League Park
 * - align="center"
 * Toledo Maroons (0-2-0) || 0 || Buffalo All-Americans (4-0-0) || 38 || Canisius Field
 * - align="center"
 * Canton Bulldogs (3-0-1) || 20 || Dayton Triangles (2-0-2) || 20 || Triangle Park
 * - align="center"
 * Chicago Cardinals (1-1-1) || 0 || Rock Island Independents (4-1-0) || 7 || Douglas Park
 * - align="center"
 * Decatur Staleys (4-0-0) || 10 || Chicago Tigers (1-1-1) || 0 || Cubs Park
 * - align="center"
 * Columbus Panhandles (0-4-0) || 0 || Detroit Heralds (2-1-0) || 6 || Mack Park
 * - align="center"
 * Syracuse Stars (0-1-0) || 7 || Rochester Jeffersons (3-0-1) || 21 || Rochester Baseball Park
 * - bgcolor="#D0E7FF"