November 25, 1920

! colspan="8" align="center" | November 28, 1920
 * - bgcolor="#D0E7FF"
 * colspan="8" align="center" | Week 10
 * - bgcolor="#efefef"
 * - align="center"
 * Akron Pros (8-0-1) || 14 || Dayton Triangles (5-2-2) || 0 || Triangle Park
 * - align="center"
 * Cleveland Tigers (2-4-2) || 0 || Buffalo All-Americans (8-1-0) || 7 || Buffalo Baseball Park
 * - align="center"
 * Decatur Staleys (9-1-1) || 6 || Chicago Cardinals (6-1-1) || 7 || Normal Park
 * - align="center"
 * Thorn Tornadoes (0-1-1) || 0 || Chicago Tigers (2-5-1) || 27 || Cubs Park
 * - align="center"
 * Lansing Oldsmobile (0-1-1) || 0 || Detroit Heralds (2-3-2) || 0 || Mack Park
 * - align="center"
 * Rochester Scalpers (0-2-0) || 6 || Rochester Jeffersons (6-3-1) || 7 || Rochester Baseball Park
 * - align="center"
 * Washington and Jeffe Collegians (0-1-0) || 7 || Rock Island Independents (6-2-2) || 48 || Douglas Park
 * - bgcolor="#D0E7FF"