1959 Toronto Argonauts season

The 1959 Toronto Argonauts finished in fourth place in the Interprovincial Rugby Football Union with a 4–10–0 record and failed to make the playoffs.

Preseason
The Argonauts hosted the NFL's Chicago Cardinals on August 5 in the first of three interleague games hosted in Toronto at CNE Stadium. The Argos lost lost 55–26.