1921 TCU Horned Frogs football team

The 1921 TCU Horned Frogs football team represented Texas Christian University (TCU) in the 1921 college football season. The Horned Frogs finished the season 2–5–3 overall. The team was coached by William L. Driver in his second and final year as head coach. The Frogs played their home games at Clark Field, which was located on campus in Fort Worth, Texas.